【特徴】背景：Cell surface glycoprotein serine protease that participates in extracellular matrix degradation and involved in many cellular processes including tissue remodeling, fibrosis, wound healing, inflammation and tumor growth. Both plasma membrane and soluble forms exhibit post-proline cleaving endopeptidase activity, with a marked preference for Ala/Ser-Gly-Pro-Ser/Asn/Ala consensus sequences, on substrate such as alpha-2-antiplasmin SERPINF2 and SPRY2. Degrade also gelatin, heat-denatured type I collagen, but not native collagen type I and IV, vibronectin, tenascin, laminin, fibronectin, fibrin or casein. Have also dipeptidyl peptidase activity, exhibiting the ability to hydrolyze the prolyl bond two residues from the N-terminus of synthetic dipeptide substrates provided that the penultimate residue is proline, with a preference for Ala-Pro, Ile-Pro, Gly-Pro, Arg-Pro and Pro-Pro. Natural neuropeptide hormones for dipeptidyl peptidase are the neuropeptide Y (NPY), peptide YY (PYY), substance P (TAC1) and brain natriuretic peptide 32 (NPPB).【仕様】種由来：Mouse発現宿主：E.coli純度：>90% as determined by reducing SDS-PAGE.遺伝子構造：A DNA sequence encoding the Mouse FAP protein (P97321) (26L-349G) was expressed with a polyhistidine tag at the N-terminus.別名（遺伝子名）：170 kDa melanoma membrane bound gelatinase,170 kDa melanoma membrane-bound gelatinase,DPPIV,FAP,FAPA,Fibroblast activation protein alpha,Integral membrane serine protease,SEPR,Seprase,FAPalpha,SIMPアミノ酸配列：26L-349GアクセッションＮｏ．：P97321タグ種類：N/C-Hisエンドトキシン濃度：Not tested.分子量：38kDa組成：Lyophilized from sterile PBS, pH 7.4保存条件：Samples are stable for up to twelve months from date of receipt at -70℃.Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.メーカーマニュアルリンク：https://u2.elabscience.com/viewpdf-447183-elabscience-PKSM500005.pdfサイズ：100ugこの商品は法規制を確認しておりません。（法規制によって販売できない場合もございます）